Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Withaferin A attenuates ovarian cancer-induced cardiac cachexia.

PloS one - 1 Jan 2020

Kelm Natia Q, Straughn Alex R, Kakar Sham S

Abstract excerpt

Cachexia is a common multifactorial syndrome in the advanced stages of cancer and accounts for approximately 20-30% of all cancer-related fatalities. In addition to the progressive loss of skeletal muscle mass, cancer results in impairments in cardiac function. We recently demonstrated that WFA attenuates the cachectic skeletal muscle phenotype induced by ovarian cancer. The purpose of this study was to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cachexia
Share to Cell Line, Tumor
Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diastole

Share to Myocardium

Share to Ovarian Neoplasms

Share to Systole

Source

Open in PubMed Open full text

Identifiers

PMID: 32722688
DOI: 10.1371/journal.pone.0236680
PMCID: PMC7386592

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Withaferin A attenuates ovarian cancer-induced cardiac cachexia.PMID 32722688Read ↗

Cardiac Atrophy, Dysfunction, and Metabolic Impairments: A Cancer-Induced Cardiomyopathy Phenotype.Semantic proximity Read ↗

Cardiac atrophy, dysfunction, and metabolic impairments: a cancer-induced heart failure phenotypeSemantic proximity Read ↗

Evidence for cardiac atrophic remodeling in cancer-induced cachexia in miceSemantic proximity Read ↗

Regulating Sirtuin 3-mediated mitochondrial dynamics through vanillic acid improves muscle atrophy in cancer-induced cachexiaSemantic proximity Read ↗

Separating anorexia -dependent and -independent effects in cancer cachexiaSemantic proximity Read ↗

Progressive development of melanoma-induced cachexia differentially impacts organ systems in miceSemantic proximity Read ↗

Regulation of the bi-directional cross-talk between ovarian cancer cells and adipocytes by SPARCSemantic proximity Read ↗

Impaired Barrier Integrity of the Skeletal Muscle Vascular Endothelium Drives Progression of Cancer CachexiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.