Article

Unacylated Ghrelin Counteracts Contractile and Mitochondrial Dysfunction in Cancer Cachexia

2025-05-04

Abstract excerpt

<h4>Background</h4> Cancer cachexia is a complex metabolic syndrome that severely impacts patient mobility, treatment strategies, and quality of life. However, no treatments are available to mitigate the debilitating consequences of cancer cachexia. Unacylated ghrelin (UnAG), the main circulating form of ghrelin, enhances muscle growth and mitochondrial function in various diseases, but its effects in cancer cach...

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Literature Corpus work: f0a6c2c3-5605-5db8-ba0a-ab812f58cb1e
DOI: 10.1101/2025.04.29.649515

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