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Article

Evidence for cardiac atrophic remodeling in cancer-induced cachexia in mice

5 Aug 2011

Abstract excerpt

Cachexia is a common complication in cancer patients, which dramatically reduces quality of life and survival. In contrast to the well-studied feature of skeletal muscle loss, alterations in cardiac muscle are unclear. Recently, we reported that heart contractile function was significantly impaired in mice with colon-26 (C26) tumors, a widely used rodent model of cancer cachexia. In the present study, we...

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Identifiers

PMID: 21822537
DOI: 10.3892/ijo.2011.1150

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