Article

Complete Genomic Screen in Late-Onset Familial Alzheimer Disease

1997-10-15

Abstract excerpt

Context. —Four genetic loci have been identified as contributing to Alzheimer disease (AD), including the amyloid precursor protein gene, the presenilin 1 gene, the presenilin 2 gene, and the apolipoprotein E gene, but do not account for all the genetic risk for AD. Objective. —To identify additional genetic risk factors for late-onset AD. Design. —A complete genomic screen was performed (N=280 markers). Critical...

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Literature Corpus work: bb2bf18c-e297-5f38-b6f3-a3100301bd93
DOI: 10.1001/jama.1997.03550150041033

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