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Article

Full genome screen for Alzheimer disease: Stage II analysis*

8 Mar 2002

Abstract excerpt

We performed a two-stage genome screen to search for novel risk factors for late-onset Alzheimer disease (AD). The first stage involved genotyping 292 affected sibling pairs using 237 markers spaced at approximately 20 cM intervals throughout the genome. In the second stage, we genotyped 451 affected sibling pairs (ASPs) with an additional 91 markers, in the 16 regions where the multipoint LOD score was greater...

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PMID: 11857588
DOI: 10.1002/ajmg.10183

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