Article

Mapping SARS-CoV-2 Nucleocapsid Function with Nanobodies

2026-01-27

Abstract excerpt

The SARS-CoV-2 nucleocapsid (N) protein is essential for viral RNA packaging, replication, and immune modulation. Despite its central role, the mechanistic contributions of its individual domains, the N-terminal domain (NTD), C-terminal domain (CTD), and the intrinsically flexible linker (LINK), remain poorly defined, largely due to the protein’s structural complexity. In this study, we developed a panel of twelve...

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Literature Corpus work: bb28a527-c3c2-5771-882f-154af46627bd
DOI: 10.64898/2026.01.26.701894

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