Article

Design, synthesis and cellular characterization of a new class of IPMK kinase inhibitors

2024-05-14

Abstract excerpt

<h4>ABSTRACT</h4> Many genetic studies have established the kinase activity of inositol phosphate multikinase (IPMK) is required for the synthesis of higher-order inositol phosphate signaling molecules, the regulation of gene expression and control of the cell cycle. These genetic studies await orthogonal validation by specific IPMK inhibitors, but no such inhibitors have been synthesized. Here, we report complet...

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Literature Corpus work: bb22ecf2-4086-54ac-8974-5d2a2b37fd56
DOI: 10.1101/2024.05.09.593371

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