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HRMAS 13 C NMR and genome-scale metabolic modeling identify threonine as a preferred dual redox substrate for Clostridioides difficile

2023-09-18

Abstract excerpt

Stickland-fermenting Clostridia preferentially ferment amino acids to generate energy and anabolic substrates for growth. In gut ecosystems, these species prefer dual redox substrates, particularly mucin-abundant leucine. Here, we establish how theronine, a more prevalent, mucin-abundant substrate, supports dual redox metabolism in the pathogen Clostridioides difficile . Real-time, High-Resolution Magic Angle Sp...

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Literature Corpus work: bb1e501b-6187-558a-986b-e47dff94d0c7
DOI: 10.1101/2023.09.18.558167

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HRMAS 13 C NMR and genome-scale metabolic modeling identify threonine as a preferred dual redox substrate for Clostridioides difficileDOI 10.1101/2023.09.18.558167Read

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HRMAS <sup>13</sup> C NMR and genome-scale metabolic modeling identify threonine as a preferred dual redox substrate for <i>Clostridioides difficile</i>

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