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Dual metabolomic profiling uncovers <i>Toxoplasma</i> manipulation of the host metabolome and the discovery of a novel parasite metabolic capability

2018-11-05

Abstract excerpt

The obligate intracellular parasite Toxoplasma gondii is auxotrophic for several key metabolites and must scavenge these from the host. It is unclear how Toxoplasma manipulates host metabolism for its overall growth rate and non-essential metabolites. To address this question, we measured changes in the joint host-parasite metabolome over a time course of infection. Host and parasite transcriptomes were simultan...

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Literature Corpus work
badacbca-4fac-5794-9f43-7e4e626f6ef9
DOI
10.1101/463075
Open publication

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Dual metabolomic profiling uncovers <i>Toxoplasma</i> manipulation of the host metabolome and the discovery of a novel parasite metabolic capabilityDOI 10.1101/463075
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