Article

<i>Clostridioides difficile</i> -mucus interactions encompass shifts in gene expression, metabolism, and biofilm formation

2024-02-01

Abstract excerpt

<h4>ABSTRACT</h4> In a healthy colon, the stratified mucus layer serves as a crucial innate immune barrier to protect the epithelium from microbes. Mucins are complex glycoproteins that serve as a nutrient source for resident microflora and can be exploited by pathogens. We aimed to understand how the intestinal pathogen, Clostridioides diffiicile , independently uses or manipulates mucus to its benefit, without...

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Literature Corpus work: b131c1c9-d6a6-5b8b-9e1c-35580719a9ba
DOI: 10.1101/2024.02.01.578425

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