Article

A molecularly engineered lectin destroys EGFR and inhibits the growth of non-small cell lung cancer

2024-03-20

Abstract excerpt

Survival rates for non-small cell lung cancer (NSCLC) remain low despite the advent of novel therapeutics. Tyrosine kinase inhibitors (TKIs) targeting mutant epidermal growth factor receptor (EGFR) in NSCLC have significantly improved mortality but are plagued with challenges--they can only be used in the small fraction of patients who have susceptible driver mutations, and resistance inevitably develops. Aberrant...

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Identifiers and source

Literature Corpus work: bb152553-727e-5a07-8692-40569ee4423e
DOI: 10.1101/2024.03.18.585535

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