Article
Asparagine-linked glycosylation protein 1 (ALG1) promotes aggressive phenotypes of lung adenocarcinoma cells, A549, via modulating N-linked glycosylation and ER-Stress.
Glycoconjugate journal - 1 Dec 2025
Piriyapairoje Kanadit, Baro Marta, Katoch Aanchal, De Muth Bryce, Villanti Ludovica, Saengboonmee Charupong, Wongkham Sopit, Contessa Joseph N, Phoomak Chatchai
Abstract excerpt
Glycosylation plays a critical role in various biological processes and is essential for cell survival. Aberrant glycosylation has been implicated in numerous diseases, including cancer. Lung cancer remains the leading cause of cancer-related mortality worldwide. The correlation between lung cancer progression and abnormal glycosylation has been demonstrated previously. Asparagine-linked glycosylation protein 1...
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