Article

A Temporal Transcriptional Map of Human Natural Killer Cell Differentiation

2019-05-07

Abstract excerpt

Natural killer cell repertoires are functionally diversified as a result of differentiation, homeostatic receptor-ligand interactions and adaptive responses to viral infections. However, the regulatory gene-circuits that define the manifold cell states and drive NK cell differentiation have not been clearly resolved. Here, we performed single-cell RNA sequencing of 26,506 cells derived from sorted phenotypically-d...

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Literature Corpus work: babcd4f2-0a4a-5ca8-91b5-3f2c564626f8
DOI: 10.1101/630657

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