Article

Pan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference mapping

2023-10-30

Abstract excerpt

The functional diversity of natural killer (NK) cell repertoires stems from differentiation, homeostatic receptor-ligand interactions, and adaptive-like responses to viral infections. Here, we generated a single-cell transcriptional reference map of healthy human blood and tissue-derived NK cells, with temporal resolution and fate-specific expression of gene regulator networks defining NK cell differentiation. Usi...

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Literature Corpus work: 33faac31-2bbe-52ca-952a-7f7bbc5b6cfa
DOI: 10.1101/2023.10.26.564050

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