Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Diversity of human NK cell developmental pathways defined by single-cell analyses.

Current opinion in immunology - 1 Feb 2022

Seo Seungmae, Mace Emily M

Abstract excerpt

Human natural killer (NK) and innate lymphoid cells (ILCs) include diverse specialized phenotypic and functional subsets that reflect their roles as innate immune effector cells present in tissue and circulation. In recent years, significant advances have been made in better defining their tissue resident phenotypes, developmental pathways, and phenotypic plasticity. Here we offer a brief review of new insights...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Differentiation
Share to Immunity, Innate
Share to Killer Cells, Natural

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Phenotype

Share to Single-Cell Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 34861544
DOI: 10.1016/j.coi.2021.11.001
PMCID: PMC8901532

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Diversity of human NK cell developmental pathways defined by single-cell analyses.PMID 34861544Read ↗

High-Dimensional Single-Cell Analysis of Natural Killer Cell Heterogeneity in Human BloodSemantic proximity Read ↗

Emerging insights into natural killer cells in human peripheral tissues.Semantic proximity Read ↗

Methods for Isolating and Defining Single-Cell Transcriptomes of Tissue-Resident Human NK Cells.Semantic proximity Read ↗

Single-Cell RNA-Seq Analysis Uncovers Distinct Functional Human NKT Cell Sub-Populations in Peripheral BloodSemantic proximity Read ↗

A Temporal Transcriptional Map of Human Natural Killer Cell DifferentiationSemantic proximity Read ↗

Single-cell Transcriptomics Reveal Different Maturation Stages and Sublineages Commitment of Human Thymic Invariant Natural Killer T cellsSemantic proximity Read ↗

Peripheral NK cell phenotypes: multiple changing of faces of an adapting, developing cell.Semantic proximity Read ↗

Single cell resolution analysis of multi-tissue derived human iNKT cells reveals novel transcriptional paradigmsSemantic proximity Read ↗

Human natural killer cell development in secondary lymphoid tissues.Semantic proximity Read ↗

T-BET and EOMES sustain mature human NK cell identity and antitumor functionSemantic proximity Read ↗

Distinct tissue-dependent composition and gene expression of human fetal innate lymphoid cellsSemantic proximity Read ↗

Unraveling NK cell heterogeneity through single-cell sequencing: insights from physiological and tumor contexts for clinical applicationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.