Unraveling NK cell heterogeneity through single-cell sequencing: insights from physiological and tumor contexts for clinical applications

Abstract excerpt

Natural killer cells (NK cells) are important immune cells within the tumor microenvironment (TME) and are considered the first line of defense in tumor immunity. Although many studies have focused on the role of NK cells in tumor therapy, the heterogeneity of NK cells complicates the investigation of the complex mechanisms within the tumor microenvironment. Single-cell sequencing technology, with its...

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