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The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency

2022-05-02

Abstract excerpt

<h4>ABSTRACT</h4> NK cells are innate lymphocytes that eliminate virus-infected and cancer cells by cytotoxicity and cytokine secretion. In addition to circulating NK cells, distinct tissue-resident NK subsets have been identified in various organs. Although transcription factors regulating NK cell development and function have been extensively studied in mice, the role of RUNX2 in these processes has not been in...

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Literature Corpus work
ddb7c296-dbfe-5e88-a6cd-256c4479535e
DOI
10.1101/2022.05.02.490285
Open publication

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The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residencyDOI 10.1101/2022.05.02.490285
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