Article

Single-cell Transcriptomics Reveal Different Maturation Stages and Sublineages Commitment of Human Thymic Invariant Natural Killer T cells

2022-08-11

Abstract excerpt

<h4>Summary</h4> Invariant natural killer T (iNKT) cells are a subset of heterogenous T-cells with potent cytotoxic and immunomodulatory properties. During thymic development, murine iNKT cells go through different maturation stages and differentiate into distinct sublineages, namely iNKT1, iNKT2, and iNKT17 cells. To define maturation stages and to assess sublineage commitment of human iNKT cells during thymic d...

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Literature Corpus work: 43556cb6-01ba-54c8-98b4-265edcc22539
DOI: 10.1101/2022.08.10.503443

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