Revolutionizing large-scale DNA synthesis with microchip-based massive in parallel synthesis system

Abstract excerpt

DNA synthesis serves as the fundamental enabling technology of engineering biology, aiming to provide DNA molecules of designed composition, length, and complexity at scale and low cost. Current high-throughput DNA synthesis technologies rely on intricate chip manufacturing and microfluidic systems to provide large-scale synthetic oligonucleotides, at the expense of low concentration and limited compatibility in t...

Topics

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• Computer Simulation
• CRISPR-Associated Protein 9
• Genes, Synthetic
• Genetic Variation
• High-Throughput Nucleotide Sequencing
• Oligonucleotide Array Sequence Analysis
• Oligonucleotides
• Sequence Analysis, DNA

Identifiers and source

Literature Corpus work

ba928354-8b7f-5190-adb4-fb141f215458

DOI

10.1101/2024.10.30.619547