Article

FAM21 is critical for TLR2-CLEC4E-mediated dendritic cell function against <i>Candida albicans</i>

2022-02-17

Abstract excerpt

FAM21 (family with sequence similarity 21) is a component of the Wiskott–Aldrich syndrome protein and SCAR homologue (WASH) protein complex that mediates actin polymerization at endosomal membranes to facilitate sorting of cargo-containing vesicles out of endosomes. To study the function of FAM21 in vivo , we generated conditional knockout (cKO) mice in the C57BL/6 background in which FAM21 was specifically knock...

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Literature Corpus work: ba7bbfc7-d614-5b6a-8e6e-76d720b1f90a
DOI: 10.1101/2022.02.16.480635

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