Article

A Genome-wide CRISPR Screen Identifies WDFY3 as a Novel Regulator of Macrophage Efferocytosis

2022-01-22

Abstract excerpt

<h4>Abstracts</h4> Phagocytic clearance of dying cells, termed efferocytosis, must occur efficiently to maintain homeostasis and prevent disease. Yet, our understanding of this important biological process remains incomplete. To search for novel regulators of efferocytosis, we performed a FACS-based genome-wide CRISPR knockout screen in primary murine macrophages. We identified a novel role for WDFY3 in efferocyt...

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Literature Corpus work: 19435f82-1665-5454-bfbc-1eff94d0e532
DOI: 10.1101/2022.01.21.477299

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