Article

Bile acid-CoA:amino acid N-acyltransferase gene knockout alters early life development, the gut microbiome and reveals unusual bile acid conjugates in mice

2022-04-10

Abstract excerpt

<h4>ABSTRACT</h4> Bile acids are steroid detergents in bile that contribute to fat absorption, cell signaling and microbiome interactions in mammals. The final step in their synthesis is amino acid conjugation with either glycine or taurine to a cholic acid or chenodeoxycholic acid backbone in the liver by the enzyme bile acid-CoA:amino acid N-acyltransferase (BAAT). Here, we describe the microbial, chemical, and...

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Literature Corpus work: ba7a6c07-0db0-5fc4-a8e7-ef18f4716865
DOI: 10.1101/2022.04.10.487642

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Bile acid-CoA:amino acid N-acyltransferase gene knockout alters early life development, the gut microbiome and reveals unusual bile acid conjugates in miceDOI 10.1101/2022.04.10.487642Read

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