Article

Spatial heterogeneity of T cell repertoire across NSCLC tumors, tumor edges, adjacent and distant lung tissues

2022-10-17

Abstract excerpt

<h4>Background</h4> A better understanding of the T cells in lung cancer and their distribution across tumor-adjacent lungs and the peripheral blood is needed to improve efficacy and minimize toxicity from immunotherapy to lung cancer patients. <h4>Methods</h4> Here, we performed CDR3β TCR sequencing of 143 samples from 21 patients with early-stage NSCLC including peripheral blood mononuclear cells, tumor, tumor e...

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Literature Corpus work: ba4b89ae-e130-5ff2-a036-aee5d10e6737
DOI: 10.1101/2022.10.14.22281040

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