Article

Integrative phenotypic and genomic analyses reveal strain-dependent responses to acute ozone exposure and their associations with airway macrophage transcriptional activity

2021-01-31

Abstract excerpt

Acute ozone (O 3 ) exposure is associated with multiple adverse cardiorespiratory outcomes, the severity of which varies across human populations and rodent models from diverse genetic backgrounds. However, molecular determinants of response, including biomarkers that distinguish which individuals will develop more severe injury and inflammation ( i.e. , high responders), are poorly characterized. Here, we expos...

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Literature Corpus work: 5b3958d2-ded4-5ba9-8836-c4a799bfb405
DOI: 10.1101/2021.01.29.428733

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