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Article

Pan-cancer analysis of whole genomes.

Nature - 1 Feb 2020

Abstract excerpt

Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome scale1-3. Here we report the integrative analysis of 2,658 whole-cancer genomes and their matching normal tissues across 38 tumour types from the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Cancer Genome Consortium (ICGC)...

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PMID: 32025007
DOI: 10.1038/s41586-020-1969-6
PMCID: PMC7025898

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