Article
Role of DJ-1 in Parkinson's disease.
Journal of molecular neuroscience : MN - 1 Jan 2006
Lev Nirit, Roncevic Dusan, Roncevich Dusan, Ickowicz Debby, Melamed Eldad, Offen Daniel
Abstract excerpt
Parkinson's disease (PD), one of the most common neurodegenerative diseases, is a multifactorial disease caused by both genetic and environmental factors. Although most patients suffering from PD have a sporadic disease, several genetic causes have been identified in recent years, including alpha-synuclein, parkin, PINK1, dardarin (LRRK2), and DJ-1. DJ-1 deletions and point mutations have been found worldwide,...
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