Article

Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1

2022-06-07

Abstract excerpt

<h4>Background: </h4> Extracranial arteriovenous malformations (AVMs) are characterized by anomalous arterial-to-venous connections, aberrant angiogenesis, local inflammation and hypoxia, and disorganized histological architecture; however, the precise molecular perturbations leading to this phenotype remain elusive. We hypothesized that extracranial AVM tissue would demonstrate deregulation of the TGF-β/BMP signa...

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Literature Corpus work: ba17269c-b448-5a40-9cf6-1ddeccb5ce5b
DOI: 10.21203/rs.3.rs-1703368/v1

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