Article
TGF-β-Induced Endothelial-Mesenchymal Transition in Fibrotic Diseases
17 Oct 2017
Abstract excerpt
Fibrotic diseases are characterized by net accumulation of extracellular matrix proteins in affected organs leading to their dysfunction and ultimate failure. Myofibroblasts have been identified as the cells responsible for the progression of the fibrotic process, and they originate from several sources, including quiescent tissue fibroblasts, circulating CD34⁺ fibrocytes and the phenotypic conversion of various...
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