Article

Macrophage are the principal reservoir and sustain high virus loads in rhesus macaques after the depletion of CD4+ T cells by a highly pathogenic simian immunodeficiency virus/HIV type 1 chimera (SHIV): Implications for HIV-1 infections of humans

2001-01-02

Abstract excerpt

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b9f9f13a-c806-5006-b91e-dfbba642f7bf
DOI: 10.1073/pnas.021551798

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Macrophage are the principal reservoir and sustain high virus loads in rhesus macaques after the depletion of CD4+ T cells by a highly pathogenic simian immunodeficiency virus/HIV type 1 chimera (SHIV): Implications for HIV-1 infections of humansDOI 10.1073/pnas.021551798Read

Macrophages in Progressive Human Immunodeficiency Virus/Simian Immunodeficiency Virus InfectionsSemantic proximity Read

HIV and SIV infection: the role of cellular restriction and immune responses in viral replication and pathogenesis.Semantic proximity Read

A New Type of Nonsuppressible Viremia Produced by HIV-Infected MacrophageSemantic proximity Read

Longitudinal transcriptomic analysis of SIV-infected rhesus macaques reveals peripheral immune dynamics throughout untreated SIV infection and long-term antiretroviral therapySemantic proximity Read

HIV pathogenesis: dynamics and genetics of viral populations and infected cells.Semantic proximity Read

Rapid disease progression to AIDS due to Simian immunodeficiency virus infection of macaques: host and viral factors.Semantic proximity Read

Microglia and macrophages alterations in the CNS during acute SIV infection: A single-cell analysis in rhesus macaquesSemantic proximity Read

Human TRIM5α: Autophagy Connects Cell-Intrinsic HIV-1 Restriction and Innate Immune Sensor FunctioningSemantic proximity Read

Macrophages and HIV-1Semantic proximity Read

Microglia and macrophages alterations in the CNS during acute SIV infection: a single-cell analysis in rhesus macaquesSemantic proximity Read

Amino acid deletions are introduced into the V2 region of gp120 during independent pathogenic simian immunodeficiency virus/HIV chimeric virus (SHIV) infections of rhesus monkeys generating variants that are macrophage tropic.Semantic proximity Read

Derivation and Characterization of Pathogenic Transmitted/Founder Molecular Clones from Simian Immunodeficiency Virus SIVsmE660 and SIVmac251 following Mucosal Infection.Semantic proximity Read