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Article

HIV and SIV infection: the role of cellular restriction and immune responses in viral replication and pathogenesis.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 May 2009

Williams Kenneth C, Burdo Tricia H

Abstract excerpt

The human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) have a long biological history. Both viruses evolved from Africa and remnants of them can be found in the 'fossil record' of several species in which they are not endemic. SIV remains endemic in several species of monkeys in Africa where it does not cause immune deficiency. HIV and SIV actively replicate within humans and Asian...

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Identifiers

PMID: 19400864
DOI: 10.1111/j.1600-0463.2009.02450.x
PMCID: PMC2739573

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