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Article

Type I and III IFN-mediated antiviral actions counteracted by SARS-CoV-2 proteins and host inherited factors.

Cytokine & growth factor reviews - 1 Apr 2021

Quarleri Jorge, Delpino M Victoria

Abstract excerpt

SARS-CoV-2 is a recently identified coronavirus accountable for the current pandemic disease known as COVID-19. Different patterns of disease progression infer a diverse host immune response, with interferon (IFN) being pivotal. IFN-I and III are produced and released by virus-infected cells during the interplay with SARS-CoV-2, thus establishing an antiviral state in target cells. However, the efficacy of IFN...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33608189
DOI: 10.1016/j.cytogfr.2021.01.003
PMCID: PMC7871890

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