Article

A microengineered collagen scaffold for generating a polarized crypt-villus architecture of human small intestinal epithelium

2019-08-17

Abstract excerpt

The human small intestinal epithelium possesses a distinct crypt-villus architecture and tissue polarity in which proliferative cells reside inside crypts while differentiated cells are localized to the villi. Indirect evidence has shown that the processes of differentiation and migration are driven in part by biochemical gradients of factors that specify the polarity of these cellular compartments; however, direc...

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Literature Corpus work: b9afc23b-d278-5ed3-abd1-42842400dee5
DOI: 10.17615/k4tv-qt25

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