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Intestinal organoid modeling: bridging the gap from experimental model to clinical translation

1 Mar 2024

Abstract excerpt

The 3D culture of intestinal organoids entails embedding isolated intestinal crypts and bone marrow mesenchymal stem cells within a growth factor-enriched matrix gel. This process leads to the formation of hollow microspheres with structures resembling intestinal epithelial cells, which are referred to as intestinal organoids. These structures encompass various functional epithelial cell types found in the small...

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PMID: 38496762
DOI: 10.3389/fonc.2024.1334631

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