Article
Crypt-Villus Scaffold Architecture for Bioengineering Functional Human Intestinal Epithelium
3 Oct 2022
Abstract excerpt
Crypt-villus architecture in the small intestine is crucial for the structural integrity of the intestinal epithelium and maintenance of gut homeostasis. We utilized three-dimensional (3D) printing and inverse molding techniques to form three-dimensional (3D) spongy scaffold systems that resemble the intestinal crypt-villus microarchitecture. The scaffolds consist of silk fibroin protein with curved lumens with...
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