Article

Bioengineered human colon organoids with <i>in vivo</i> -like complexity and function

2023-10-06

Abstract excerpt

<h4>Summary</h4> Organoids and microphysiological systems, such as organs-on-a-chip, have emerged as powerful tools for modeling human gut physiology and disease in vitro . However, although physiologically relevant, these systems often lack the environmental milieu, spatial organization, cell-type diversity, and maturity necessary for mimicking adult human intestinal mucosa. To instead generate models closely r...

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Literature Corpus work: b887f4f1-0dfe-50ea-a0e4-8a4c2a06156a
DOI: 10.1101/2023.10.05.560991

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