An iPSC-derived small intestine-on-chip with self-organizing epithelial, mesenchymal, and neural cells

Abstract excerpt

Human induced pluripotent stem cell (hiPSC)-derived intestinal organoids are valuable tools for researching developmental biology and personalized therapies, but their closed topology and relative immature state limit applications. Here, we use organ-on-chip technology to develop a hiPSC-derived intestinal barrier with apical and basolateral access in a more physiological in vitro microenvironment. To replicate...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to 3D Printing in Biomedical Research
• Share to Cancer Cells and Metastasis
• Share to Pluripotent Stem Cells Research