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Intestinal Stem Cell-on-Chip to Study Human Host-Microbiota Interaction

6 Dec 2021

Abstract excerpt

The gut is a tubular organ responsible for nutrient absorption and harbors our intestinal microbiome. This organ is composed of a multitude of specialized cell types arranged in complex barrier-forming crypts and villi covered by a mucosal layer controlling nutrient passage and protecting from invading pathogens. The development and self-renewal of the intestinal epithelium are guided by niche signals controlling...

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PMID: 34938299
DOI: 10.3389/fimmu.2021.798552

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