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A novel membrane-on-chip guides morphogenesis for the reconstruction of the intestinal crypt-villus axis

20 Jul 2024

Abstract excerpt

Abstract Reconstructing the microscale villous organisation and functionality of the small intestine is essential for developing in vitro platforms tailored for absorption studies as well as for investigating intestinal morphogenesis in development and disease. However, the current fabrication techniques able to mimic the villus-crypt axis poses significant challenges in terms of reconstruction of the complex 3D...

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PMID: 39029501
DOI: 10.1088/1758-5090/ad6599

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