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Article

The ERI-6/7 helicase acts at the first stage of an siRNA amplification pathway that targets recent gene duplications.

PLoS genetics - 1 Nov 2011

Fischer Sylvia E J, Montgomery Taiowa A, Zhang Chi, Fahlgren Noah, Breen Peter C, Hwang Alexia, Sullivan Christopher M, Carrington James C, Ruvkun Gary

Abstract excerpt

Endogenous small interfering RNAs (siRNAs) are a class of naturally occuring regulatory RNAs found in fungi, plants, and animals. Some endogenous siRNAs are required to silence transposons or function in chromosome segregation; however, the specific roles of most endogenous siRNAs are unclear. The helicase gene eri-6/7 was identified in the nematode Caenorhabditis elegans by the enhanced response to exogenous...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22102828
DOI: 10.1371/journal.pgen.1002369
PMCID: PMC3213143

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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