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Article

Autologous tumor-immune effusion co-cultures enable ex vivo functional profiling of radiotherapy-immunotherapy combinations

2026-01-12

Abstract excerpt

<title>Abstract</title> <p> Background Currently, radiotherapy-immunotherapy (RT-IO) combinations provide limited and heterogeneous benefit in human solid cancers and are frequently selected empirically, partly because human models that preserve native, autologous tumor-immune interactions are lacking. We developed patient-derived autologous tumor-immune effusion co-cultures (PATEC) as an <italic>ex vivo</ital...

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Literature Corpus work
b938e848-800b-59ec-a270-363b6071e6f8
DOI
10.21203/rs.3.rs-8516163/v1
Open publication

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Autologous tumor-immune effusion co-cultures enable ex vivo functional profiling of radiotherapy-immunotherapy combinationsDOI 10.21203/rs.3.rs-8516163/v1
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