Article

Carbon ion irradiation plus CTLA4 blockade elicits therapeutic immune responses in a murine tumor model

2022-07-22

Abstract excerpt

Radiotherapy can act as an in situ vaccine thereby activating tumor-specific immune responses that prevent tumor outgrowth in treated patients. While carbon ion radiotherapy has shown superior biophysical properties over conventional photon irradiation, the immunological effects induced have remained largely uncovered. The combination of radiotherapy with immune checkpoint inhibition (radioimmunotherapy) aims at...

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Literature Corpus work: bfb919ed-219b-579a-8790-ccf5c28b0fc2
DOI: 10.1101/2022.07.22.500608

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