Article
A single cell atlas reveals distinct immune landscapes in transplant and primary tumors that determine response or resistance to immunotherapy
2020-03-12
Abstract excerpt
Despite impressive responses in some patients, immunotherapy fails to cure most cancer patients. Preclinical studies indicate that radiotherapy synergizes with immunotherapy, promoting radiation-induced antitumor immunity. Nearly all preclinical immunotherapy studies utilize transplant tumor models, but cure rates of transplant tumor models treated with immunotherapy often overestimate patient responses. Here, we...
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Identifiers and source
- Literature Corpus work
- 1780436f-bb25-5e33-9c8b-eb7393077620
- DOI
- 10.1101/2020.03.11.978387