Article

Patient-derived functional immuno-oncology platform identifies responders to ATR inhibitor and immunotherapy combinations in ovarian cancer

2024-02-19

Abstract excerpt

Responses to single agent immunotherapies have remained modest in high-grade serous ovarian cancer (HGSC), suggesting the need for combination treatments. Identifying clinically effective immunotherapy combinations (IC) requires pre-clinical testing using models representing the patient-specific immune microenvironment. Here, we established a functional immuno-oncology platform for high-throughput and functional t...

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Literature Corpus work: 5484254e-6215-5fbe-9842-13ffe5344434
DOI: 10.1101/2024.02.15.579904

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