Article

Monogenic Syndromes as a Cause of Adverse Drug Reactions in the Russian Population

2026-02-17

Abstract excerpt

<h4>Introduction</h4> Adverse drug reactions (ADRs) remain a major public health issue, and genetic factors contribute importantly to interindividual variability in drug response. Pharmacogenetic testing helps reduce ADR risk by optimizing drug selection and dosage, particularly in monogenic disorders. <h4>Material and Methods</h4> Whole-exome sequencing of 6,739 samples from the Russian population was performed...

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Literature Corpus work: b922dae2-00f1-5d0f-bdd1-bcc2045ea5e9
DOI: 10.64898/2026.02.13.26346297

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