Article
The genetics of pro-arrhythmic adverse drug reactions.
British journal of clinical pharmacology - 1 Apr 2014
Petropoulou Evmorfia, Jamshidi Yalda, Behr Elijah R
Abstract excerpt
Ventricular arrhythmia induced by drugs (pro-arrythmia) is an uncommon event, whose occurrence is unpredictable but potentially fatal. The ability of a variety of medications to induce these arrhythmias is a significant problem facing the pharmaceutical industry. Genetic variants have been shown to play a role in adverse events and are also known to influence an individual's optimal drug dose. This review...
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