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Pharmacogenomic analysis and clinical annotation of 635 patients.

Personalized medicine - 1 Jun 2025

Bağcı Özkan, Şanlıtürk Batuhan, Özdemir Ebru Marzioğlu, Koçak Nadir, Cora Tülin

Abstract excerpt

AIM: In this study, we aimed to reveal the sequence analysis of 69 pharmacogenes in 635 patients and the clinical explanation of variants. MATERIALS AND METHODS: Genomic DNA was isolated from peripheral blood of patients. Next-Generation Sequence analysis and bioinformatic analysis were performed to identify 69 pharmacogene variants. Variants with clinical annotation were identified. RESULTS: Analysis of 69...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40247430
DOI: 10.1080/17410541.2025.2493606

Genes

CYP2C19
DPYD
MTHFR
RYR1
UGT1A1
VKORC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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