Pharmacogenetics and adverse drug reactions.

Abstract excerpt

Polymorphisms in the genes that code for drug-metabolising enzymes, drug transporters, drug receptors, and ion channels can affect an individual's risk of having an adverse drug reaction, or can alter the efficacy of drug treatment in that individual. Mutant alleles at a single gene locus are the best studied individual risk factors for adverse drug reactions, and include many genes coding for drug-metabolising...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Drug-Related Side Effects and Adverse Reactions
• Share to Mutation
• Share to Pharmaceutical Preparations