Article
Drug-induced arrhythmia: pharmacogenomic prescribing?
European heart journal - 1 Jan 2013
Behr Elijah R, Roden Dan
Abstract excerpt
Drug-induced Torsades de Pointes is a rare, unpredictable, and life-threatening serious adverse event. It can be caused by both cardiac and non-cardiac drugs and has become a major issue in novel drug development and for the regulatory authorities. This review describes the problem, predisposing factors, and the underlying genetic predisposition as it is understood currently. The future potential for...
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