Article

SARS-CoV-2 Delta Spike Protein Enhances the Viral Fusogenicity and Inflammatory Cytokine Production

2021-11-30

Abstract excerpt

The Delta variant is now the most dominant and virulent SARS-CoV-2 variant of concern (VOC). In this study, we investigated several virological features of Delta spike protein (SP<sub>Delta</sub>), including protein maturation and its impact on viral entry of cell-free pseudotyped virus, cell-cell fusion ability and its induction of inflammatory cytokine production in human macrophages and dendritic cells. The res...

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Literature Corpus work: b8fe8b37-f6db-51bb-b8c0-88bce210b6b0
DOI: 10.2139/ssrn.3974934

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