Article
Membrane fusion and immune evasion by the spike protein of SARS-CoV-2 Delta variant.
Science (New York, N.Y.) - 10 Dec 2021
Zhang Jun, Xiao Tianshu, Cai Yongfei, Lavine Christy L, Peng Hanqin, Zhu Haisun, Anand Krishna, Tong Pei, Gautam Avneesh, Mayer Megan L, Walsh Richard M, Rits-Volloch Sophia, Wesemann Duane R, Yang Wei, Seaman Michael S, Lu Jianming, Chen Bing
Abstract excerpt
The Delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has outcompeted previously prevalent variants and become a dominant strain worldwide. We report the structure, function, and antigenicity of its full-length spike (S) trimer as well as those of the Gamma and Kappa variants, and compare their characteristics with the G614, Alpha, and Beta variants. Delta S can fuse membranes more...
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